【佳學(xué)基因檢測】cDNA微陣列：基因特征的鑒定及其在臨床實踐中的應(yīng)用

靶向藥一旦停藥會怎樣省錢要點

查重分析《腫瘤治療效果與基因檢測結(jié)果的相關(guān)性》《J BUON》在?2007 Sep;12 Suppl 1:S39-44發(fā)表了一篇題目為《cDNA微陣列：基因特征的鑒定及其在臨床實踐中的應(yīng)用》腫瘤靶向藥物治療基因檢測臨床研究文章。該研究由Zvonko Magic,?Sinisa Radulovic,?Mirjana Brankovic-Magic等完成。促進了腫瘤的正確治療與個性化用藥的發(fā)展，進一步強調(diào)了基因信息檢測與分析的重要性。

腫瘤靶向藥物及正確治療臨床研究內(nèi)容關(guān)鍵詞：

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腫瘤靶向治療基因檢測臨床應(yīng)用結(jié)果

人類基因組測序為醫(yī)學(xué)帶來了新的后基因組時代。一種新的微陣列技術(shù)代表了一種新的遺傳平臺，它被廣泛用于彌合基因序列和功能之間的差距?；旧希褂眠@種技術(shù)，可以同時測量基因組中幾乎所有基因的活性。這些實驗的結(jié)果是斑點的亮度因基因而異，對應(yīng)于所檢查基因的轉(zhuǎn)錄活性。它可以創(chuàng)建實驗來尋找其表達與腫瘤的存在、從良性疾病進展到惡性疾病或從低級別到高級別惡性腫瘤的進展相關(guān)的基因。可以更具體地識別腫瘤類型，并且可以使用基因表達的差異來檢測已經(jīng)證明與轉(zhuǎn)移風險增加相關(guān)的基因表達變化的腫瘤。基因表達譜還將幫助臨床醫(yī)生就癌癥患者的賊佳治療做出決定。

腫瘤發(fā)生與反復(fù)轉(zhuǎn)移國際數(shù)據(jù)庫描述：

Sequencing of human genome introduced the new postgenomic era in medicine. A novel microarray technology represents a novel genetic platform which is being widely exploited to bridge the gap between gene sequence and function. Basically, with this technique it is possible to simultaneously measure the activity of virtually all genes in the genome. The result of these experiments are spots whose brightness varies from gene to gene corresponding to the transcriptional activity of the examined genes. It makes it possible to create experiments looking for genes whose expression correlates with the presence of tumor, with progression from a benign to a malignant condition, or with progression from a low grade to high grade malignancy. Tumor types can be more specifically identified, and differences in gene expression can be used to detect tumors that already demonstrate gene expression changes associated with increased risk of metastasis. Gene expression profiles will also help clinicians make decisions about the optimal treatment of cancer patients.