【佳學(xué)基因檢測(cè)】1型神經(jīng)纖維瘤病兒童的運(yùn)動(dòng)時(shí)間不足

腫瘤基因檢測(cè)的費(fèi)用大概多少錢回答

研究癌癥的早期發(fā)現(xiàn)及檢測(cè)獲悉《Res Dev Disabil》在.?2014 Nov;35(11):3131-8.發(fā)表了一篇題目為《1型神經(jīng)纖維瘤病兒童的運(yùn)動(dòng)時(shí)間不足》腫瘤靶向藥物治療基因檢測(cè)臨床研究文章。該研究由Julie Debrabant?,?Ellen Plasschaert?,?Karen Caeyenberghs?,?Guy Vingerhoets?,?Eric Legius?,?Sandra Janssens?,?Hilde Van Waelvelde?等完成。促進(jìn)了腫瘤的正確治療與個(gè)性化用藥的發(fā)展，進(jìn)一步強(qiáng)調(diào)了基因信息檢測(cè)與分析的重要性。

腫瘤轉(zhuǎn)移惡化的基因根源臨床研究?jī)?nèi)容關(guān)鍵詞：

兒童運(yùn)動(dòng)功能,發(fā)育時(shí)間線, 1型神經(jīng)纖維瘤病,反應(yīng)時(shí)間

腫瘤靶向治療基因檢測(cè)臨床應(yīng)用結(jié)果

型神經(jīng)纖維瘤病 (NF1) 是賊常見的單基因疾病之一，影響精細(xì)和視覺運(yùn)動(dòng)技能。這項(xiàng)病例對(duì)照研究調(diào)查了運(yùn)動(dòng)計(jì)時(shí)作為 NF1 兒童可能存在的相關(guān)表現(xiàn)缺陷。對(duì) 20 名 NF1 兒童（平均年齡 9 歲 7 個(gè)月）和 20 名年齡和性別匹配的典型發(fā)育 (TD) 兒童進(jìn)行了視覺運(yùn)動(dòng)反應(yīng)時(shí)間 (VRT) 測(cè)試。使用視覺-運(yùn)動(dòng)整合的 Beery-Buktenica 發(fā)育測(cè)試 (Beery VMI) 評(píng)估復(fù)制和跟蹤性能。與 TD 兒童相比，患有 NF1 的兒童對(duì)時(shí)間預(yù)測(cè)性刺激的反應(yīng)時(shí)間 (RT) 增加，而對(duì)不可預(yù)測(cè)性刺激的反應(yīng)時(shí)間在各組之間沒有差異。在與 Beery VMI 復(fù)制和追蹤結(jié)果顯著相關(guān)的預(yù)測(cè)刺激下，由 RT 索引的運(yùn)動(dòng)時(shí)間減少。運(yùn)動(dòng)時(shí)間不足作為一種實(shí)際癥狀可能有助于進(jìn)一步研究 NF1 相關(guān)運(yùn)動(dòng)障礙的發(fā)病機(jī)制和開發(fā)更有效的治療方法。電機(jī)開發(fā)；電機(jī)正時(shí)； 1型神經(jīng)纖維瘤??；反應(yīng)時(shí)間。

腫瘤發(fā)生與反復(fù)轉(zhuǎn)移國(guó)際數(shù)據(jù)庫描述：

Neurofibromatosis type 1 (NF1) is one of the most common single-gene disorders affecting fine and visual-motor skills. This case-control study investigated motor timing as a possible related performance deficit in children with NF1. A visual-motor reaction time (VRT) test was administered in 20 NF1 children (mean age 9 years 7 months) and 20 age- and gender-matched typically developing (TD) children. Copying and tracing performance were evaluated using the Beery-Buktenica Developmental Test of Visual-Motor Integration (Beery VMI). Children with NF1 responded with an increased reaction time (RT) to temporally predictive stimuli compared to TD children, whereas RT at unpredictive stimuli did not differ between groups. Motor timing indexed by the RT decrease at predictive stimuli significantly associated with the Beery VMI copy and tracing outcomes. Deficient motor timing as an actual symptom may add to further research on the pathogenesis of NF1-associated motor impairment and the development of more effective treatment.Keywords:?Children; Motor development; Motor timing; Neurofibromatosis type 1; Reaction time.