【佳學基因檢測】1型神經(jīng)纖維瘤病兒童的運動時間不足

腫瘤基因檢測的費用大概多少錢回答

研究癌癥的早期發(fā)現(xiàn)及檢測獲悉《Res Dev Disabil》在.?2014 Nov;35(11):3131-8.發(fā)表了一篇題目為《1型神經(jīng)纖維瘤病兒童的運動時間不足》腫瘤靶向藥物治療基因檢測臨床研究文章。該研究由Julie Debrabant?,?Ellen Plasschaert?,?Karen Caeyenberghs?,?Guy Vingerhoets?,?Eric Legius?,?Sandra Janssens?,?Hilde Van Waelvelde?等完成。促進了腫瘤的正確治療與個性化用藥的發(fā)展，進一步強調了基因信息檢測與分析的重要性。

腫瘤轉移惡化的基因根源臨床研究內容關鍵詞：

兒童運動功能,發(fā)育時間線, 1型神經(jīng)纖維瘤病,反應時間

腫瘤靶向治療基因檢測臨床應用結果

型神經(jīng)纖維瘤病 (NF1) 是賊常見的單基因疾病之一，影響精細和視覺運動技能。這項病例對照研究調查了運動計時作為 NF1 兒童可能存在的相關表現(xiàn)缺陷。對 20 名 NF1 兒童（平均年齡 9 歲 7 個月）和 20 名年齡和性別匹配的典型發(fā)育 (TD) 兒童進行了視覺運動反應時間 (VRT) 測試。使用視覺-運動整合的 Beery-Buktenica 發(fā)育測試 (Beery VMI) 評估復制和跟蹤性能。與 TD 兒童相比，患有 NF1 的兒童對時間預測性刺激的反應時間 (RT) 增加，而對不可預測性刺激的反應時間在各組之間沒有差異。在與 Beery VMI 復制和追蹤結果顯著相關的預測刺激下，由 RT 索引的運動時間減少。運動時間不足作為一種實際癥狀可能有助于進一步研究 NF1 相關運動障礙的發(fā)病機制和開發(fā)更有效的治療方法。電機開發(fā)；電機正時； 1型神經(jīng)纖維瘤病；反應時間。

腫瘤發(fā)生與反復轉移國際數(shù)據(jù)庫描述：

Neurofibromatosis type 1 (NF1) is one of the most common single-gene disorders affecting fine and visual-motor skills. This case-control study investigated motor timing as a possible related performance deficit in children with NF1. A visual-motor reaction time (VRT) test was administered in 20 NF1 children (mean age 9 years 7 months) and 20 age- and gender-matched typically developing (TD) children. Copying and tracing performance were evaluated using the Beery-Buktenica Developmental Test of Visual-Motor Integration (Beery VMI). Children with NF1 responded with an increased reaction time (RT) to temporally predictive stimuli compared to TD children, whereas RT at unpredictive stimuli did not differ between groups. Motor timing indexed by the RT decrease at predictive stimuli significantly associated with the Beery VMI copy and tracing outcomes. Deficient motor timing as an actual symptom may add to further research on the pathogenesis of NF1-associated motor impairment and the development of more effective treatment.Keywords:?Children; Motor development; Motor timing; Neurofibromatosis type 1; Reaction time.