【佳學(xué)基因檢測(cè)】基因檢測(cè)生殖系突變與乳腺癌風(fēng)險(xiǎn)患者的針對(duì)性的定制管理——考慮手術(shù)預(yù)防乳腺癌的選擇

品牌基因檢測(cè)聯(lián)系方式—客觀性

開(kāi)題評(píng)估醫(yī)學(xué)博士年度腫瘤匯報(bào)《腫瘤突變基因檢測(cè)與個(gè)性化治療方案的制定》《Breast J》在.?2009 Sep-Oct;15 Suppl 1:S76-80.發(fā)表了一篇題目為《基因檢測(cè)生殖系突變與乳腺癌風(fēng)險(xiǎn)患者的針對(duì)性的定制管理——考慮手術(shù)預(yù)防乳腺癌的選擇》腫瘤靶向藥物治療基因檢測(cè)臨床研究文章。該研究由Edibaldo Silva?等完成。促進(jìn)了腫瘤的正確治療與個(gè)性化用藥的發(fā)展，進(jìn)一步強(qiáng)調(diào)了基因信息檢測(cè)與分析的重要性。

更多腫瘤靶向藥物的選擇與提供臨床研究?jī)?nèi)容關(guān)鍵詞：

乳腺癌,乳房切除術(shù),乳腺切除術(shù),保留乳房,基因檢測(cè),人工智能,算法

腫瘤靶向治療基因檢測(cè)臨床應(yīng)用結(jié)果

由于乳腺癌致病基因的早期發(fā)現(xiàn)和發(fā)生風(fēng)險(xiǎn)的破密解碼，賊近的報(bào)告顯示乳腺癌患者越來(lái)越多地使用乳房切除術(shù)，否則可以保留乳房。同樣，其他報(bào)告記錄了因單側(cè)乳腺癌接受對(duì)側(cè)預(yù)防性乳房切除術(shù)的女性人數(shù)增加。越來(lái)越多的 MRI 使用、不充分的風(fēng)險(xiǎn)咨詢(xún)和患者恐懼助長(zhǎng)了這些趨勢(shì)。在正確的基因檢測(cè)后，充分和高效的風(fēng)險(xiǎn)評(píng)估和遺傳咨詢(xún)對(duì)于對(duì)這些人進(jìn)行適當(dāng)和個(gè)性化的治療是必不可少的。在所有這些情況下，此類(lèi)咨詢(xún)應(yīng)在患者接受任何手術(shù)干預(yù)之前進(jìn)行。乳腺癌基因解碼基因檢測(cè)提出了一種算法，該算法允許有序地選擇可能從這種積極的手術(shù)干預(yù)中受益的患者。

腫瘤發(fā)生與反復(fù)轉(zhuǎn)移國(guó)際數(shù)據(jù)庫(kù)描述：

Recent reports have documented the increasing use of mastectomy in women with breast cancer otherwise amenable to breast conservation. Similarly, other reports document an increase in the number of women undergoing contra-lateral prophylactic mastectomy for a single unilateral breast cancer. These trends are abetted by increasing use of MRI, inadequate risk counseling, and patient fear. Adequate and reliable risk assessment and genetic counseling are indispensable for the appropriate and personalized treatment of these individuals. In all of these instances, such counseling should be instituted well before the patients are submitted to any surgical intervention. An algorithm is presented which permits the orderly selection of patients who may benefit from such aggressive surgical intervention.